UMR7216 Epigenetics and Cell Fate :
The field of epigenetics has attracted much attention in recent years. It has evolved from the early questions that Conrad Waddington posed about the relationship between genotype and phenotype during development, towards mechanistic understanding of the importance of DNA methylation, chromatin structure and non-coding RNAs in regulating genome plasticity. These recent intellectual and technological advances have changed the way we think about the genome and how we explore the role of transcriptional programs in cell fate decisions during development and in response to stress environments. The unit of Epigenetics and Cell Fate brings together researchers who are fascinated by the molecular mechanisms that determine cellular differentiation programs. The research centre creates an exciting opportunity to combine experimental approaches and cellular models to explore the link between epigenetics and cell fate.
LABEX Laureates :
The Labex project "Who Am I ?" coordinated by Jonathan Weitzman and Catherine Dargemont (IJM) was one of 71 projects selected in the second call for Laboratoire d’Excellence. The consortium brings together labs from Paris 7 and Paris 5, including biologists, physicists and social scientists, to address issues of identity at the molecular, cellular and population levels. The project will be funded over an 8-year period and hopes to stimulate interdisciplinary research at our universities.